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internalisation of receptors model
Many transmembrane receptors (GCPRs) undergo internalisation which is induced by an agonist (ligand). During this process they migrate from the cell surface to the cytoplasm.

The internalisation of receptors model examines the dynamics of internalisation of receptors in response to ligands.


applications
inflammatory disease (Crohn’s disease, recto-colitis….)
metabolic diseases (diabetes…)
neurodegenerative disease (Alzheimer’s disease…)
receptor trafficking