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human primary peripheral blood mononuclear cell model
Biovays has developed a highly relevent model for the analysis of the immunomodulatory effects of candidates. This model is based on specific cells isolated from human PBMCs.

Human primary peripheral blood mononuclear cells (PBMCs) are a critical component of the immune system for fighting infection and adapting to the presence intruders.


applications
study of immunomodulatory effects of candidates on human cells derived from PBMCs (dendritic cells, macrophages)
study of anti-inflammatory effects of candidates
cytokine and chemokine production
inflammatory diseases: inflammatory bowel diseases (IBS), ulcerative colitis (UC, Crohn’s disease)
allergy and auto-immune diseases
immune-endothelial interactions